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Qu'est-ce (qui) est epistasis - définition
epistasis
![The top row indicates interactions between two genes that show either ('''a''') additive effects, ('''b''') positive epistasis or ('''c''') reciprocal sign epistasis. Below are [[fitness landscape]]s which display greater and greater levels of global epistasis between large numbers of genes. Purely additive interactions lead to a single smooth peak ('''d'''); as increasing numbers of genes exhibit epistasis, the landscape becomes more rugged ('''e'''), and when all genes interact epistatically the landscape becomes so rugged that mutations have seemingly random effects ('''f''').](https://commons.wikimedia.org/wiki/Special:FilePath/Epistasis and landscapes.png?width=200 "The top row indicates interactions between two genes that show either ('''a''') additive effects, ('''b''') positive epistasis or ('''c''') reciprocal sign epistasis. Below are [[fitness landscape]]s which display greater and greater levels of global epistasis between large numbers of genes. Purely additive interactions lead to a single smooth peak ('''d'''); as increasing numbers of genes exhibit epistasis, the landscape becomes more rugged ('''e'''), and when all genes interact epistatically the landscape becomes so rugged that mutations have seemingly random effects ('''f''').")
PHENOMENON WHERE THE EFFECT OF ONE GENE (LOCUS) IS DEPENDENT ON THE PRESENCE OF ONE OR MORE MODIFIER GENES, ITS GENETIC BACKGROUND
Genetic interactions; Non-allelic gene interaction; Genetic interaction; Gene interaction; Epistatic Gene; Epistatic gene; Epistasis, genetic; Intragenic complementation; Modifier gene; Epistatic; Genetic suppression; Suppressor gene; Epistasy; Transcriptional suppressor; Genetic background; Intragenic epistasis; Intergenic epistasis; Suppressor (genetics); Modifier genes
[?'p?st?s?s]
¦ noun Genetics the suppression by a gene of the effect of another gene.
Derivatives
epistatic ??p?'stat?k adjective
Origin
C19: from Gk, lit. 'stoppage'.
Epistasis
PHENOMENON WHERE THE EFFECT OF ONE GENE (LOCUS) IS DEPENDENT ON THE PRESENCE OF ONE OR MORE MODIFIER GENES, ITS GENETIC BACKGROUND
Genetic interactions; Non-allelic gene interaction; Genetic interaction; Gene interaction; Epistatic Gene; Epistatic gene; Epistasis, genetic; Intragenic complementation; Modifier gene; Epistatic; Genetic suppression; Suppressor gene; Epistasy; Transcriptional suppressor; Genetic background; Intragenic epistasis; Intergenic epistasis; Suppressor (genetics); Modifier genes
Epistasis is a phenomenon in genetics in which the effect of a gene mutation is dependent on the presence or absence of mutations in one or more other genes, respectively termed modifier genes. In other words, the effect of the mutation is dependent on the genetic background in which it appears.
Wikipédia
Epistasis
Epistasis is a phenomenon in genetics in which the effect of a gene mutation is dependent on the presence or absence of mutations in one or more other genes, respectively termed modifier genes. In other words, the effect of the mutation is dependent on the genetic background in which it appears.
